DOSAGE FORM DEVELOPMENT

The selection of a final dosage form is driven by the project’s commercial needs, and properties of the drug substance. Ascendia offers a range of final dosage form options for our client’s development projects.

For oral dosage formulation, we have the capability to granulate, blend, and roller compact to make tablet and capsule batches for immediate release and modified release applications. We can fluid-bed coat particles and provide small capsule batches for controlled release products. We can provide taste masked pediatric formulations, including suspensions and orally disintegrating tablets. We have small to production-scale equipment for filling and banding of liquid and powder formulation into gelatin and HPMC capsules.

For parenteral formulations, we have the capability to produce nano-emulsions using high shear homogenization. We manufacture nano-particles using ball milling techniques. These formulations can be administered as permanent suspensions for injection, or we have the capability to lyophilize if physical stability is an issue and provide powders for reconstitution.

For topical formulations we can formulate creams or ointments for application to the skin or mucous membranes. Our nano-emulsions are suitable for ophthalmic drop application to the eye. We can manufacture suspensions for nasal sprays.

Let Ascendia help you determine what the best final dosage form option is for your pharmaceutical development project.