October 1, 2014

Nano-Emulsion Formulations for Injection & Oral Administration

Nanoemulsion FormulationsOil-in-water emulsions, which are composed of oil droplets dispersed in an aqueous continuous phase, can provide unique solutions for overcoming drug solubility and stability problems. In general, emulsions have many practical applications in the agriculture, food, cosmetic, pesticide, and pharmaceutical industries.1 One of the uses of emulsions is to deliver active pharmaceutical ingredients (APIs) in topical, oral, nasal, ophthalmic, or injectable dosage forms.

Although a number of lipid-based nanoemulsion pharmaceutical products have been marketed in the past 20 years, there are fewer examples of oil-in-water emulsion products. Examples include Diprivan® (propofol), an injectable anesthetic, and Restasis® (cyclosporin), an opthalmic drop for dry-eye syndrome.

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